VialPNC-27 (10mg)
PNC-27
$119.00per unit · 3ml
PNC-27 is a membrane-active peptide containing an HDM-2 binding domain fused to a membrane-penetrating sequence, studied in cellular and oncology research models.
Third-party tested · Purity 99.7% · For laboratory research use only.
- Purity
- 99.7%
- Form
- Powder (lyophilized)
- Size
- 3ml
Mechanism of Action
PNC-27 is researched for its ability to bind HDM-2 expressed on certain cell membranes, leading to membrane disruption in cell-culture models.
Research Areas
- ●Cellular membrane research
- ●Oncology cell-culture models
- ●p53/HDM-2 pathway studies
- ●Selective cytotoxicity research
Selected References
- Sarafraz-Yazdi E, et al. Anticancer peptide PNC-27 induces tumor cell necrosis. Proc Natl Acad Sci. 2010.